Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis

@article{Kmpers2009TimeCO,
  title={Time course of angiopoietin-2 release during experimental human endotoxemia and sepsis},
  author={Philipp K{\"u}mpers and Matijs van Meurs and Sascha David and Grietje Molema and Johan Bijzet and Alexander Lukasz and Frank Biertz and Hermann Haller and Jan G Zijlstra},
  journal={Critical Care},
  year={2009},
  volume={13},
  pages={R64 - R64}
}
INTRODUCTION Endothelial activation leading to vascular barrier breakdown denotes a devastating event in sepsis. Angiopoietin (Ang)-2, a circulating antagonistic ligand of the endothelial specific Tie2 receptor, is rapidly released from Weibel-Palade and has been identified as a non-redundant gatekeeper of endothelial activation. We aimed to study: the time course of Ang-2 release during human experimental endotoxemia; the association of Ang-2 with soluble adhesion molecules and inflammatory… CONTINUE READING
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References

Publications referenced by this paper.
SHOWING 1-10 OF 35 REFERENCES

Angiopoietin signalling in critical illness; a future target

  • M. van Meurs, P. Kumpers, +5 authors J. G. Zijlstra
  • Crit Care
  • 2009
2 Excerpts

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