Time course gene expression data in colon of mice after exposure to food-grade E171

@article{Proquin2018TimeCG,
  title={Time course gene expression data in colon of mice after exposure to food-grade E171},
  author={H{\'e}lo{\"i}se Proquin and Marlon J. A. Jetten and Marloes C. M. Jonkhout and Luis Guillermo Gardu{\~n}o-Balderas and Jacob J. Bried{\'e} and Theo M. de Kok and Yolanda Irasema Chirino and Henk van Loveren},
  journal={Data in Brief},
  year={2018},
  volume={16},
  pages={531 - 600}
}
We investigated gene expression responses in BALB/c mice exposed by gavage to 5 mg/kg bw/day of E171 for 2, 7, 14 and 21 days. Food additive E171 (titanium dioxide) has been shown to induce oxidative stress and DNA damage in vitro as well as facilitating growth of colorectal tumours in vivo. Full genome expression changes of the colon of mice were investigated by using Agilent SurePrint G3 mouse Gene exp 60kv2 microarrays slides. The data presented in this DiB include all differentially… Expand
2 Citations
Manually curated transcriptomics data collection for toxicogenomic assessment of engineered nanomaterials.
TLDR
This work curated a collection of homogenized transcriptomics data from human, mouse and rat ENM exposures in vitro and in vivo including the physicochemical characteristics of the ENMs used in each study. Expand
EFSA statement on the review of the risks related to the exposure to the food additive titanium dioxide (E 171) performed by the French Agency for Food, Environmental and Occupational Health and Safety (ANSES)
TLDR
EFSA concludes that the ANSES opinion published in April 2019 does not identify any major new findings that would overrule the conclusions made in the previous two scientific opinions on the safety of titanium dioxide (E 171) as a food additive issued by the EFSA ANS Panel in 2016 and 2018. Expand

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