Time-course gait analysis of hemiparkinsonian rats following 6-hydroxydopamine lesion

@article{Hsieh2011TimecourseGA,
  title={Time-course gait analysis of hemiparkinsonian rats following 6-hydroxydopamine lesion},
  author={Tsung-Hsun Hsieh and Jia-Jin J. Chen and Li-Hsien Chen and Pei-Tzu Chiang and Hsiao-Yu Lee},
  journal={Behavioural Brain Research},
  year={2011},
  volume={222},
  pages={1-9}
}
Gait disturbances similar to those of human Parkinson's disease (PD) can be observed in animals after administration of neurotoxin 6-hydroxydopamine (6-OHDA) to induce unilateral nigrostriatal dopamine depletion. However, the relationship between gait disturbances and dopamine depletion following 6-OHDA infusion has not been determined. The present study investigated the longitudinal changes of spatiotemporal gait patterns using a walkway system to acquire footprints and lateral limb images… Expand
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