Time course for development of respiratory compensation in metabolic acidosis.

@article{Asch1969TimeCF,
  title={Time course for development of respiratory compensation in metabolic acidosis.},
  author={Morris J. Asch and Ralph B. Dell and Gardner S. Williams and Murray G Cohen and Robert W. Winters},
  journal={The Journal of laboratory and clinical medicine},
  year={1969},
  volume={73 4},
  pages={
          610-5
        }
}
Abstract The time course for the development of respiratory compensation in metabolic acidosis has been studied in unanesthetized dogs receiving large loads of hydrochloric acid. The fall in PaCO 2 for a given fall in whole blood base excess is greater in sustained, i.e., longer than 6 hours, than in acute, i.e., up to 3 hours, acidosis. These results suggest that there is a time lag in the development of full respiratory compensation in metabolic acidosis; this lag is analogous to the lag in… CONTINUE READING
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