Time and temperature dependence of granulocyte damage by leucotoxic supernatants from Pasteurella haemolytica A1.

@article{Styrt1990TimeAT,
  title={Time and temperature dependence of granulocyte damage by leucotoxic supernatants from Pasteurella haemolytica A1.},
  author={B Styrt and Robert D. Walker and Linda D Dahl and Allyson Potter},
  journal={Journal of general microbiology},
  year={1990},
  volume={136 11},
  pages={2173-8}
}
Bacterial exotoxins may contribute to the pathogenic potential of micro-organisms through interactions with cells of the host defence system as well as by directly damaging host tissue. The present studies were designed to explore mechanisms of interaction between bovine granulocytes and the leucotoxin produced by Pasteurella haemolytica, a major cause of bovine respiratory disease. Leucotoxin-containing supernatant from P. haemolytica A1 caused rapid cell death in isolated bovine granulocytes… CONTINUE READING

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