Time- and pH-Dependent Copper Binding to Aβ(1–16) Peptide: An Electrospray Ionization-Mass Spectrometric Approach

@article{Manea2014TimeAP,
  title={Time- and pH-Dependent Copper Binding to Aβ(1–16) Peptide: An Electrospray Ionization-Mass Spectrometric Approach},
  author={Marilena Manea and Gitta Schlosser and Manuela Murariu},
  journal={International Journal of Peptide Research and Therapeutics},
  year={2014},
  volume={21},
  pages={125-131}
}
An elevated concentration of copper ions in the brain of Alzheimer’s disease patients has been reported in many studies and might be associated with an increased aggregation of β-amyloid (Aβ) peptides. In the present work, the interaction with copper ions of a model β-amyloid peptide, Aβ(1–16), was investigated by electrospray ionization-mass spectrometry… CONTINUE READING