Time- and dose rate-related effects of internal (177)Lu exposure on gene expression in mouse kidney tissue.


INTRODUCTION The kidneys are the dose-limiting organs in some radionuclide therapy regimens. However, the biological impact of internal exposure from radionuclides is still not fully understood. The aim of this study was to examine the effects of dose rate and time after i.v. injection of (177)LuCl3 on changes in transcriptional patterns in mouse kidney… (More)
DOI: 10.1016/j.nucmedbio.2014.07.010


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