Time Domain Fluorescent Diffuse Optical Tomography: analytical expressions.

@article{Lam2005TimeDF,
  title={Time Domain Fluorescent Diffuse Optical Tomography: analytical expressions.},
  author={Stephen W. K. Lam and Fr{\'e}d{\'e}ric Lesage and Xavier Intes},
  journal={Optics express},
  year={2005},
  volume={13 7},
  pages={2263-75}
}
Light propagation in tissue is known to be favored in the Near Infrared spectral range. Capitalizing on this fact, new classes of molecular contrast agents are engineered to fluoresce in the Near Infrared. The potential of these new agents is vast as it allows tracking non-invasively and quantitatively specific molecular events in-vivo. However, to monitor the bio-distribution of such compounds in thick tissue proper physical models of light propagation are necessary. To recover 3D… CONTINUE READING