Time Dependent Distribution of MicroRNA 144 after Intravenous Delivery.

Abstract

BACKGROUND miR-144 has potential benefits in protecting against myocardial ischemia and suppression of tumor growth. We have previously shown that a single intravenous injection of miR-144 provides potent cardioprotection, but its kinetics and distribution are not known. METHODS Single stranded mature miR-144 or Cy3-labelled-miR-144 was delivered into C57… (More)

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