Time-Dependent Diffusion MRI in Cancer: Tissue Modeling and Applications


In diffusion weighted imaging (DWI), the apparent diffusion coefficient (ADC) has been recognized as a useful and sensitive surrogate for cell density, paving the way for non-invasive tumor staging, and characterization of treatment efficacy in cancer. However, microstructural parameters, such as cell size, density and/or compartmental diffusivities affect… (More)
DOI: 10.3389/fphy.2017.00058

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