Time Course of Brain Network Reconfiguration Supporting Inhibitory Control

@article{Popov2018TimeCO,
  title={Time Course of Brain Network Reconfiguration Supporting Inhibitory Control},
  author={Tzvetan Popov and Britta U. Westner and Rebecca Levin Silton and Sarah M. Sass and Jeffrey M. Spielberg and Brigitte Rockstroh and Wendy Heller and Gregory A. Miller},
  journal={The Journal of Neuroscience},
  year={2018},
  volume={38},
  pages={4348 - 4356}
}
Hemodynamic research has recently clarified key nodes and links in brain networks implementing inhibitory control. Although fMRI methods are optimized for identifying the structure of brain networks, the relatively slow temporal course of fMRI limits the ability to characterize network operation. The latter is crucial for developing a mechanistic understanding of how brain networks shift dynamically to support inhibitory control. To address this critical gap, we applied spectrally resolved… 

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References

SHOWING 1-10 OF 63 REFERENCES
Flexible brain network reconfiguration supporting inhibitory control
TLDR
It is shown via network analysis that global brain connectivity patterns change when inhibitory demands increase, including greater communication efficiency and robustness against disruption, and the connectivity pattern of regions previously identified as crucial for inhibitory control become more central network hubs.
The Relation of Brain Oscillations to Attentional Networks
TLDR
The attention network test is used to separate three anatomically defined brain networks that carry out the functions of alerting, orienting, and executive control of attention and found that each attentional network has a distinct set of oscillations related to its activity.
Theta oscillations mediate interaction between prefrontal cortex and medial temporal lobe in human memory.
TLDR
Cortical electrical activity from MTL, PFC, and lateral temporal lobe was recorded from implanted electrode grids in 3 epilepsy patients performing a verbal free recall task to obtain estimates of power, coherence, and Granger causality.
Theta and beta synchrony coordinate frontal eye fields and anterior cingulate cortex during sensorimotor mapping
TLDR
A role of ACC in cognitive control of frontoparietal networks is supported and it is suggested that narrow-band theta and to some extent beta rhythmic activity indexes the coordination of relevant information during periods of enhanced control demands.
A mechanism of deficient interregional neural communication in schizophrenia.
TLDR
Behavioral performance and EEG theta oscillations were examined and results suggest ACC-MFG theta power modulation as a mechanism of interference control that supports executive function and is disrupted in schizophrenia.
Prelude to and Resolution of an Error: EEG Phase Synchrony Reveals Cognitive Control Dynamics during Action Monitoring
TLDR
Oscillatory dynamics in the theta band may in part underlie a mechanism of communication between networks involved in action monitoring and cognitive control.
Midfrontal conflict-related theta-band power reflects neural oscillations that predict behavior.
TLDR
Most of the conflict-related and behaviorally relevant midfrontal EEG signal reflects a modulation of ongoing theta-band oscillations that occurs during the decision process but is not phase-locked to the stimulus or to the response.
Frequency-specific directed interactions in the human brain network for language
Significance The brain’s remarkable capacity for language requires bidirectional interactions between functionally specialized brain regions. Although the functional role of individual regions in the
Midline Frontal Cortex Low-Frequency Activity Drives Subthalamic Nucleus Oscillations during Conflict
TLDR
The cortico-subcortical circuit enabling successful choices to be made under conditions of conflict is established and support for the hypothesis that the brain uses frequency-specific channels of communication to convey behaviorally relevant information is provided.
...
...