Tiling path genomic profiling of grade 3 invasive ductal breast cancers.

@article{Natrajan2009TilingPG,
  title={Tiling path genomic profiling of grade 3 invasive ductal breast cancers.},
  author={Rachael Natrajan and Maryou B K Lambros and Socorro Mar{\'i}a Rodr{\'i}guez-Pinilla and Gema Moreno-Bueno and David Sp Tan and Caterina Marchi{\`o} and Radost Vatcheva and Sydonia Rayter and Betania Mahler-Araujo and Laura G. Fulford and Daniela Hungermann and Alan Mackay and Andreas Grigoriadis and Kerry Fenwick and Narinder Tamber and David Hardisson and Andrew N J Tutt and Jos{\'e} Antonio Gurpegui Palacios and Christopher J Lord and Horst Buerger and Alan Ashworth and Jorge S Reis-Filho},
  journal={Clinical cancer research : an official journal of the American Association for Cancer Research},
  year={2009},
  volume={15 8},
  pages={
          2711-22
        }
}
PURPOSE To characterize the molecular genetic profiles of grade 3 invasive ductal carcinomas of no special type using high-resolution microarray-based comparative genomic hybridization (aCGH) and to identify recurrent amplicons harboring putative therapeutic targets associated with luminal, HER-2, and basal-like tumor phenotypes. EXPERIMENTAL DESIGN Ninety-five grade 3 invasive ductal carcinomas of no special type were classified into luminal, HER-2, and basal-like subgroups using a… CONTINUE READING

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References

Publications referenced by this paper.
SHOWING 1-10 OF 50 REFERENCES

Integrated profiling of basal and luminal breast cancers.

  • Cancer research
  • 2007
VIEW 10 EXCERPTS
HIGHLY INFLUENTIAL

Immunohistochemical and clinical characterization of the basal-like subtype of invasive breast carcinoma.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2004
VIEW 5 EXCERPTS
HIGHLY INFLUENTIAL

Genetic characterisation of invasive breast cancer: a comparison of CGH and PCR Genomic Profiling of Grade 3 Ductal Breast Cancers www.aacrjournals.org Clin Cancer Res 2009;15(8

H Buerger, H Schmidt, +3 authors B. Brandt
  • April 15,
  • 2009
VIEW 1 EXCERPT

Basal-like breast cancer defined by five biomarkers has superior prognostic value than triple-negative phenotype.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2008

Ductal carcinoma in situ and the emergence of diversity during breast cancer evolution.

  • Clinical cancer research : an official journal of the American Association for Cancer Research
  • 2008
VIEW 2 EXCERPTS

Genomic analysis of the HER 2 / TOP 2 A amplicon in breast cancer and breast cancer cell lines

E Arriola, C Marchio, DS Tan
  • Lab Invest
  • 2008