Tight junctions between the axon and Schwann cell during PNS regeneration.

We report here that during PNS regeneration, short focal tight junctions are present at the interface of regenerating axons and Schwann cells in the distal part of the transected nerve. When regrowing axons were seen in the distal segment, focal fusions of axonal and Schwann cell membranes were observed on electron microscopy. Freeze-fracture study showed… CONTINUE READING