Tight junctions/adherens junctions: basic structure and function.

  title={Tight junctions/adherens junctions: basic structure and function.},
  author={C. Niessen},
  journal={The Journal of investigative dermatology},
  volume={127 11},
  • C. Niessen
  • Published 2007 in The Journal of investigative dermatology
Adherens and tight junctions are intercellular junctions crucial for epithelial adhesion and barrier function in a wide variety of tissues and organisms. In stratifying epithelia, such as the epidermis, the role of adherens and tight junctions was considered less important owing to the abundance of desmosomes, mediating firm mechanical stability between the cells, and to the barrier function of the stratum corneum, respectively. This view has changed in recent years because of different studies… CONTINUE READING
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