Tight junction modulation of the blood brain barrier: CNS delivery of small molecules.

Abstract

The blood brain barrier (BBB) represents a major obstacle for targeted drug delivery to the brain for the treatment of central nervous system (CNS) disorders. Significant advances in barrier research over the past decade has led to the discovery of an increasing number of structural and regulatory proteins in tight junctions (TJ) and adherens junctions (AJ… (More)
DOI: 10.1080/21688370.2015.1138017

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