Tight glycemic control reduces heart inflammation and remodeling during acute myocardial infarction in hyperglycemic patients.

@article{Marfella2009TightGC,
  title={Tight glycemic control reduces heart inflammation and remodeling during acute myocardial infarction in hyperglycemic patients.},
  author={Raffaele Marfella and Clara Di Filippo and Michele Portoghese and Franca Ferraraccio and Maria Rosaria Rizzo and Mario Siniscalchi and Emilio Musacchio and Michele D'Amico and Francesco Rossi and Guiseppe Paolisso},
  journal={Journal of the American College of Cardiology},
  year={2009},
  volume={53 16},
  pages={1425-36}
}
OBJECTIVES We analyzed the molecular mechanisms evoked by tight glycemic control during post-infarction remodeling in human hearts. BACKGROUND The molecular mechanisms by which tight glycemic control improves heart remodeling during acute myocardial infarction (AMI) are still largely unknown. METHODS Eighty-eight patients with first AMI undergoing coronary bypass surgery were studied: 38 normoglycemic patients served as the control group; hyperglycemic patients (glucose >or=140 mg/dl) were… CONTINUE READING

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Glucose - insulinpotassium therapy in patients with STsegment elevation myocardial infarction

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