Tigecycline antimicrobial activity tested against clinical bacteria from Latin American medical centres: results from SENTRY Antimicrobial Surveillance Program (2011-2014).

@article{Sader2016TigecyclineAA,
  title={Tigecycline antimicrobial activity tested against clinical bacteria from Latin American medical centres: results from SENTRY Antimicrobial Surveillance Program (2011-2014).},
  author={H{\'e}lio S. Sader and M. S. A. Castanheira and David John Farrell and Robert K. Flamm and Rodrigo Elisandro Mendes and Ronald N. Jones},
  journal={International journal of antimicrobial agents},
  year={2016},
  volume={48 2},
  pages={144-50}
}
Bacterial organisms (n = 13,494) were consecutively collected in 2011-2014 from 21 Latin American medical centres (11 nations). Antimicrobial susceptibility was determined by broth microdilution at a central laboratory. Tigecycline was very active against Gram-positive organisms, with MIC50/90 values of 0.06/0.06 µg/mL for Staphylococcus aureus (n = 2878), 0.06/0.12 µg/mL for coagulase-negative staphylococci (n = 880), 0.06/0.06 µg/mL for enterococci (n = 708) and ≤0.03/≤0.03-0.06 µg/mL for… CONTINUE READING