Tidal chain reaction and the origin of replicating biopolymers

@article{Lathe2005TidalCR,
  title={Tidal chain reaction and the origin of replicating biopolymers},
  author={Richard Lathe},
  journal={International Journal of Astrobiology},
  year={2005},
  volume={4},
  pages={19 - 31}
}
  • R. Lathe
  • Published 1 January 2005
  • Physics
  • International Journal of Astrobiology
Template-directed polymer assembly is a likely feature of prebiotic chemistry, but the product blocks further synthesis, preventing amplification and Darwinian selection. Nucleic acids are unusual because charge repulsion between opposing phosphates permits salt-dependent association and dissociation. It was postulated (Lathe, R. (2004). Fast tidal cycling and the origin of life. Icarus168, 18–22) that tides at ocean shores provide the driving force for amplification: evaporative concentration… Expand
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References

SHOWING 1-10 OF 170 REFERENCES
Fast tidal cycling and the origin of life
Replicating prebiotic polymers are thought to predate the emergence of true life-forms. The initial mode of replication, a prerequisite for Darwinian selection, is unknown, but demands an explanationExpand
Surface-promoted replication and exponential amplification of DNA analogues
TLDR
An iterative, stepwise procedure for chemical replication which permits an exponential increase in the concentration of oligonucleotide analogues, called SPREAD, which combines the advantages of solid-phase chemistry with chemical replication, and can be further developed for the non-enzymatic and enzymatic amplification of RNA, peptides and other templates. Expand
Condensation of DNA by multivalent cations: Considerations on mechanism
TLDR
It appears that the size distribution of condensed particles is determined kinetically rather than thermodynamically, and that slow condensation kinetics may be required to overcome the high activation energy of highly distorted DNA bends or kinks at the turning points of rods. Expand
Synthesis of long prebiotic oligomers on mineral surfaces
TLDR
This work describes a system that models prebiotic polymerization by the oligomerization of activated monomers—both nucleotides and amino acids, and finds that whereas the reactions in solution produce only short oligomers, the presence of mineral surfaces induces the formation of oligomers up to 55 monomers long. Expand
Synthesis of RNA oligomers on heterogeneous templates
TLDR
It is shown that heterogeneous oligocytidylates, formed by the montmorillonite clay-catalysed condensation of actuated monomers, can serve as templates for the synthesis of oligoguanylates. Expand
Polymerization on the Rocks: Theoretical Introduction
  • L. Orgel
  • Chemistry, Medicine
  • Origins of life and evolution of the biosphere
  • 2004
TLDR
It is suggested that long polymers were synthesized on the surface of minerals in a prebiotic process analogous to solid-phase synthesis, and it is shown that the average length of adsorbed oligomers at steady state depends on the balance between the rate of chain elongation and the rates of hydrolysis. Expand
Prebiotic ribose synthesis: A critical analysis
  • R. Shapiro
  • Biology
  • Origins of life and evolution of the biosphere
  • 2005
TLDR
The evidence that is currently available does not support the availability of ribose on the prebiotic earth, except perhaps for brief periods of time, in low concentration as part of a complex mixture, and under conditions unsuitable for nucleoside synthesis. Expand
Condensation of DNA by trivalent cations. 2. Effects of cation structure
TLDR
Electron microscopy is employed to examine DNA aggregates produced by three tripositively charged condensing agents, finding that ligand charge seems to be the major factor in predicting condensing power, ligand structure influences the morphology and dimensions of the particles produced. Expand
Origins of the temperature dependence of hammerhead ribozyme catalysis.
TLDR
The hammerhead ribozyme cleavage was investigated under single-turnover conditions between 0 and 60 degrees C as a model for RNA-catalyzed reactions to suggest the occurrence of a conformational change of the ribo enzyme ground state around physiological temperatures. Expand
Selective emergence and survival of early polypeptides in water
  • A. Brack
  • Chemistry, Medicine
  • Origins of life and evolution of the biosphere
  • 2006
TLDR
It is shown that N-carboxyanhydrides are good candidates for chemical selection in water and those having short linear aliphatic side-chains such asα-aminobutyric acid or norvaline are not. Expand
...
1
2
3
4
5
...