Tics and Tourette syndrome
@article{Dale2021TicsAT, title={Tics and Tourette syndrome}, author={Russell C. Dale}, journal={Journal of the Neurological Sciences}, year={2021}, volume={429} }
Tourette syndrome is a heterogeneous disorder. The genetic basis is complex, and both in utero and ex utero environmental factors may modify the phenotypic expression of the disorder. Inflammation related to aberrations in immune activation appears to play a pathogenic role in some cases. Multiple neurochemical pathways are involved. Rather than being a pure movement problem, tics are now understood to also have a sensory component. This has resulted in new psychological therapeutic strategies…
16 Citations
Tics of Trauma: Unique Case of Trauma-Associated Psychogenic Tics in an Adolescent Patient
- Psychology, MedicineCureus
- 2021
A 16-year-old girl with a history of trauma who initially presented with depression and trauma-related anxiety develops verbal and motor tic-like symptoms that worsened with stress and court proceedings, classified as psychogenic tics secondary to the trauma associated with sexual abuse.
European clinical guidelines for Tourette syndrome and other tic disorders—version 2.0. Part III: pharmacological treatment
- Psychology, MedicineEuropean Child & Adolescent Psychiatry
- 2021
Overall, treatment of TS should be individualized, and decisions based on the patient’s needs and preferences, presence of co-existing conditions, latest scientific findings as well as on the physician's preferences, experience, and local regulatory requirements are presented.
Comorbid chronic tic disorder and tourette syndrome in children requiring inpatient mental health treatment
- Medicine, PsychologyClinical child psychology and psychiatry
- 2021
In the authors' sample, comorbid CTD/TS seem to represent a marker of overall symptom severity as evidenced by longer admissions, which is significant in children needing inpatient treatment.
Incidence of Autism Spectrum Disorder in Youths Affected by Gilles de la Tourette Syndrome Based on Data from a Large Single Italian Clinical Cohort
- Psychology, MedicineBrain sciences
- 2020
The incidence of GTS and ASD comorbidity in this study was high, and this has several implications in terms of treatment and prognosis.
Enrichment and Correlation Analysis of Serum miRNAs in Comorbidity Between Arnold-Chiari and Tourette Syndrome Contribute to Clarify Their Molecular Bases
- BiologyFrontiers in Molecular Neuroscience
- 2020
The dysregulation of the miRNA set is proposed as a potential molecular tool for supporting the current diagnosis of AC, TS, and ACTS by using liquid biopsies, in an unbiased and non-invasive way.
The Histaminergic System in Neuropsychiatric Disorders
- Psychology, BiologyBiomolecules
- 2021
This review comprehensively summarize recent experimental and clinical findings on the precise role of histaminergic system in neuropsychiatric disorders, including cell-type role and its circuit bases in narcolepsy, schizophrenia, Alzheimer's disease, Tourette's syndrome and Parkinson’s disease.
Tourette syndrome research highlights from 2018
- PsychologyF1000Research
- 2019
This is the fifth yearly article in the Tourette Syndrome Research Highlights series, summarizing research from 2018 relevant to Tourette syndrome and other tic disorders. The authors briefly…
Target-Specific Effects of Deep Brain Stimulation for Tourette Syndrome: A Systematic Review and Meta-Analysis
- MedicineFrontiers in Neurology
- 2021
It is concluded that DBS is a clinically effective treatment option for patients with treatment-refractory Tourette syndrome, with all targets showing comparable improvement rates.
Psychosocial stress, self-esteem, and social adjustment: A moderated mediation analysis in Taiwanese adolescents with Tourette syndrome.
- PsychologyJournal of pediatric nursing
- 2021
Effect of Jian-Pi-Zhi-Dong Decoction on the Amino Acid Neurotransmitters in a Rat Model of Tourette Syndrome and Comorbid Anxiety Disorder
- BiologyFrontiers in Psychiatry
- 2020
The study revealed that JPZDD was effective in alleviating the behavioral symptoms of both tic and anxiety in the rat model groups, and reversed the mitochondrial dysfunction both in the striatum and cortex in affected animals.
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