Tick saliva suppresses IFN signalling in dendritic cells upon Borrelia afzelii infection.

Abstract

Type I interferons (IFN-α and IFN-β) are crucial determinants of the host immune response and tick saliva modulates this response, thus facilitating the transmission of tickborne pathogens. The current study therefore examines the effect of Ixodes ricinus tick saliva on IFN-β signalling in murine dendritic cells using lipopolysaccharide (LPS) and Borrelia… (More)
DOI: 10.1111/j.1365-3024.2011.01345.x

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