Tick-Borne Flaviviruses, with a Focus on Powassan Virus

@article{Kemenesi2018TickBorneFW,
  title={Tick-Borne Flaviviruses, with a Focus on Powassan Virus},
  author={G{\'a}bor Kemenesi and Kriszti{\'a}n B{\'a}nyai},
  journal={Clinical Microbiology Reviews},
  year={2018},
  volume={32}
}
The tick-borne pathogen Powassan virus is a rare cause of encephalitis in North America and the Russian Far East. The number of documented cases described since the discovery of Powassan virus in 1958 may be <150, although detection of cases has increased over the past decade. SUMMARY The tick-borne pathogen Powassan virus is a rare cause of encephalitis in North America and the Russian Far East. The number of documented cases described since the discovery of Powassan virus in 1958 may be <150… 
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References

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TLDR
This review provides an overview of Powassan virus, including the epidemiology, transmission, clinical disease, and diagnosis of POWV infection, and recent research developments and future priorities with regard to the disease are emphasized.
Molecular epidemiology of Powassan virus in North America
TLDR
It is confirmed that POW and DTV sequences are relatively stable over time, which suggests strong evolutionary constraint, and support field observations that suggest that tick-borne flavivirus populations are extremely stable in enzootic foci.
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TLDR
Although POWV disease is probably under-recognized, and it causes significant morbidity, and thus is an additional tick-borne emerging infectious disease entity, the basis of prevention is personal protection from ticks and reduced exposure to peridomestic wild mammals.
Stable prevalence of Powassan virus in Ixodes scapularis in a northern Wisconsin focus.
TLDR
Findings suggest stable transmission of POWV in this focus over ten years and highlight the potential for this agent to emerge as a public health concern.
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TLDR
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TLDR
Composite studies conducted annually in the Primorsky kray showed the tick-borne encephalitis virus to play the main etiological role in the group of encephalites with the spring-summer incidence and antibody to ticks, Powassan virus and both viruses simultaneously was found in patients with progredient forms of ticks and in subjects with the history of tick attachment.
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TLDR
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TLDR
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TLDR
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