Tic40, a membrane-anchored co-chaperone homolog in the chloroplast protein translocon.

@article{Chou2003Tic40AM,
  title={Tic40, a membrane-anchored co-chaperone homolog in the chloroplast protein translocon.},
  author={Ming-Lun Chou and Lynda M Fitzpatrick and S Tu and Gregory J Budziszewski and Sharon Potter-Lewis and Mitsuru Akita and Joshua Z. Levin and Kenneth Keegstra and Hsou-min Li},
  journal={The EMBO journal},
  year={2003},
  volume={22 12},
  pages={2970-80}
}
The function of Tic40 during chloroplast protein import was investigated. Tic40 is an inner envelope membrane protein with a large hydrophilic domain located in the stroma. Arabidopsis null mutants of the atTic40 gene were very pale green and grew slowly but were not seedling lethal. Isolated mutant chloroplasts imported precursor proteins at a lower rate than wild-type chloroplasts. Mutant chloroplasts were normal in allowing binding of precursor proteins. However, during subsequent… CONTINUE READING
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