Tianeptine: An Antidepressant with Memory-Protective Properties

@article{Zoladz2008TianeptineAA,
  title={Tianeptine: An Antidepressant with Memory-Protective Properties},
  author={Phillip R Zoladz and Collin R. Park and Carmen Mu{\~n}oz and Monika Fleshner and David M Diamond},
  journal={Current Neuropharmacology},
  year={2008},
  volume={6},
  pages={311 - 321}
}
The development of effective pharmacotherapy for major depression is important because it is such a widespread and debilitating mental disorder. Here, we have reviewed preclinical and clinical studies on tianeptine, an atypical antidepressant which ameliorates the adverse effects of stress on brain and memory. In animal studies, tianeptine has been shown to prevent stress-induced morphological sequelae in the hippocampus and amygdala, as well as to prevent stress from impairing synaptic… 
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