Tiagabine adjunctive therapy in children with refractory epilepsy: a single-blind dose escalating study.

Abstract

Tiagabine, a specific gamma-aminobutyric acid-uptake inhibitor, has been shown to be reasonably well tolerated and efficacious as adjunctive treatment for partial seizures in adults and is now being investigated in children. This 4-month, single-blind study evaluated the tolerability, safety and preliminary efficacy of ascending doses (0.25-1.5 mg/kg/day… (More)

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@article{Uldall2000TiagabineAT, title={Tiagabine adjunctive therapy in children with refractory epilepsy: a single-blind dose escalating study.}, author={Peter Vilhelm Uldall and Christine Bulteau and Svend Arne Pedersen and Olivier Dulac and Karsten Lyby}, journal={Epilepsy research}, year={2000}, volume={42 2-3}, pages={159-68} }