Tia1 dependent regulation of mRNA subcellular location and translation controls p53 expression in B cells

Abstract

Post-transcriptional regulation of cellular mRNA is essential for protein synthesis. Here we describe the importance of mRNA translational repression and mRNA subcellular location for protein expression during B lymphocyte activation and the DNA damage response. Cytoplasmic RNA granules are formed upon cell activation with mitogens, including stress… (More)
DOI: 10.1038/s41467-017-00454-2

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