Thyroxine control of pancreatic amylase gene expression: modulation of PTF1 binding activity.

@article{Lee1994ThyroxineCO,
  title={Thyroxine control of pancreatic amylase gene expression: modulation of PTF1 binding activity.},
  author={Ping Chuan Lee and Xiang Mao},
  journal={Molecular and cellular endocrinology},
  year={1994},
  volume={101 1-2},
  pages={287-93}
}
The role of pancreas specific transcription factor (PTF1) in thyroxine (T4) modulation of amylase gene expression in suckling rats was evaluated. Electrophoretic mobility shift assay (EMSA) was used to determine the PTF1 binding activity by the amount of a synthetic oligonucleotide containing the amylase enhancer sequence bound by nuclear protein extracts… CONTINUE READING