Thyrotropin-secreting pituitary carcinoma.

  title={Thyrotropin-secreting pituitary carcinoma.},
  author={A James Mixson and Theodore C Friedman and Daniel A. Katz and Irwin M. Feuerstein and Jeffrey K Taubenberger and Jean Colandrea and John L. Doppman and Edward H. Oldfield and Bruce D. Weintraub},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={76 2},
Pituitary tumors rarely metastasize outside the central nervous system. Of the more than 100 reported TSH-secreting adenomas, we now describe the first carcinoma. A 40-yr-old woman had transsphenoidal surgery for a large TSH-secreting pituitary adenoma in 1984. She had increased thyroid hormone levels with a TSH that varied from 16-31 microU/mL, and an unusually high alpha-subunit that ranged from 125-150 ng/mL. Because of residual tumor, she had a left craniotomy in 1985 followed by radiation… CONTINUE READING


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