Thyrotropin receptor autoantibodies are independent risk factors for Graves' ophthalmopathy and help to predict severity and outcome of the disease.

@article{Eckstein2006ThyrotropinRA,
  title={Thyrotropin receptor autoantibodies are independent risk factors for Graves' ophthalmopathy and help to predict severity and outcome of the disease.},
  author={Anja Katrin Eckstein and Marco Plicht and Hildegard Lax and Markus Neuh{\"a}user and Klaus Mann and Sebastian Lederbogen and Christian Ferdinand Reinhold Heckmann and J. Esser and Nils G. Morgenthaler},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2006},
  volume={91 9},
  pages={3464-70}
}
OBJECTIVE The objective of this study was to examine whether TSH-receptor antibody [TSH binding inhibitory antibodies (TBII)] levels are associated with the severity of Graves' ophthalmopathy (GO) over the entire course of the disease. METHODS AND PATIENTS A total of 159 patients with GO were followed for 12-24 months. One year after the first symptoms of GO, all patients were classified into mild or severe GO according to their clinical manifestations. TBII were measured every 3 months after… CONTINUE READING

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