Thyroid transcription factor-1 expression in breast carcinomas.

@article{Robens2010ThyroidTF,
  title={Thyroid transcription factor-1 expression in breast carcinomas.},
  author={Judith Robens and Lynn M. Goldstein and Allen M. Gown and Stuart J. Schnitt},
  journal={The American journal of surgical pathology},
  year={2010},
  volume={34 12},
  pages={
          1881-5
        }
}
Immunostaining for thyroid transcription factor-1 (TTF-1) is frequently used to help assess the site of origin of metastatic carcinomas. TTF-1 expression is most frequently seen in carcinomas of thyroid and lung origin. Furthermore, it has been assumed that the expression of TTF-1 in a carcinoma excludes the possibility of a breast origin. We have recently encountered in our consultation practice 4 cases of invasive breast carcinoma (confirmed by clinical findings and other immunophenotypic… CONTINUE READING

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