Thyroid status and muscle protein breakdown as assessed by urinary 3-methylhistidine excretion: study in thyrotoxic patients before and after treatment.

@article{Rodier1984ThyroidSA,
  title={Thyroid status and muscle protein breakdown as assessed by urinary 3-methylhistidine excretion: study in thyrotoxic patients before and after treatment.},
  author={Michel Rodier and Jessica L Richard and Jacques Bringer and Ghislaine Cavali{\'e} and H{\'e}l{\`e}ne Bellet and Jacques Mirouze},
  journal={Metabolism: clinical and experimental},
  year={1984},
  volume={33 1},
  pages={97-100}
}
Urinary 3-methylhistidine (3MH) excretion was studied in nine thyrotoxic patients before and after treatment. Urinary creatinine (Cr) output was also measured and was low in the thyrotoxic subjects before treatment. Thus, although urinary output of 3MH was not greater than among the control population when expressed per subject, it was significantly elevated when expressed as the ratio of 3MH to Cr; this ratio fell significantly, reaching normal control values after a euthyroid state was… CONTINUE READING