Thyroid peroxidase activity is inhibited by amino acids.

@article{Carvalho2000ThyroidPA,
  title={Thyroid peroxidase activity is inhibited by amino acids.},
  author={Denise P Carvalho and Alexandre Cestari Ferreira and Sabrina Mendes Coelho and Jos{\'e} Maria Mendes Moraes and Marcos Antonio Camacho and Doris Rosenthal},
  journal={Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas},
  year={2000},
  volume={33 3},
  pages={
          355-61
        }
}
Normal in vitro thyroid peroxidase (TPO) iodide oxidation activity was completely inhibited by a hydrolyzed TPO preparation (0.15 mg/ml) or hydrolyzed bovine serum albumin (BSA, 0.2 mg/ml). A pancreatic hydrolysate of casein (trypticase peptone, 0.1 mg/ml) and some amino acids (cysteine, tryptophan and methionine, 50 microM each) also inhibited the TPO iodide oxidation reaction completely, whereas casamino acids (0.1 mg/ml), and tyrosine, phenylalanine and histidine (50 microM each) inhibited… CONTINUE READING

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