Thyroid origin of Calcitonin

@article{Foster1964ThyroidOO,
  title={Thyroid origin of Calcitonin},
  author={Giraud V. Foster and A. Baghdiantz and M. Ashwini Kumar and Eris Hawley Slack and H. A. Soliman and Ian Macintyre},
  journal={Nature},
  year={1964},
  volume={202},
  pages={1303-1305}
}
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An unprecedented investigation of the evolution of neuropeptide copy number over a period of approximately 270 Myr is performed by analysing sequence data from over 50 ophiuroid species, with reference to a robust phylogeny, and indicates that the composition of neuroPEptide ‘cocktails’ is functionally important, but with plasticity over long evolutionary time scales.
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It is found that this explanation is too simple and that there are, in fact, 2 hormones from the parathyroid involved—parathormone, released by hypocalcemia, and a hypocalcemic factor, calcitonin, which is released by hypercalcemia.
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