233 Citations
Procalcitonin is expressed in osteoblasts and limits bone resorption through inhibition of macrophage migration during intermittent PTH treatment
- Biology, MedicineBone Research
- 2022
A potential role of osteoblast-derived ProCT is revealed in the bone microenvironment that is required to limit bone resorption during iPTH and arrests macrophage migration and causes inhibition of early but not late osteoclastogenesis.
Fasudil Ameliorates Osteoporosis Following Myocardial Infarction by Regulating Cardiac Calcitonin Secretion
- Medicine, BiologyJournal of Cardiovascular Translational Research
- 2022
It is suggested that fasudil improved MI-induced osteoporosis by promoting cardiac secreting calcitonin, and αCGRP could effectively inhibit the proliferation of primary fibroblasts treated with TGF-β.
Thermo-Sensitive mPEG-PA-PLL Hydrogel for Drug Release of Calcitonin
- Biology, Materials ScienceGels
- 2022
A thermo-sensitive polymer, mPEG-PA, modified with charged amino acid lysine was developed, which showed a promising potential for the oral delivery of peptide drugs.
ENDOCRINE TUMOURS: Calcitonin in thyroid and extra-thyroid Neuroendocrine Neoplasms: the two-faced Janus.
- Medicine, BiologyEuropean journal of endocrinology
- 2020
The gray areas in the interpretation of calcitonin measurement are examined in order to provide a tool to clarify the origin of calcitonin secretion and differentiate the behavior of the two-faced Janus of neuroendocrinology: intra-thyroid (MTC) and extra-thy thyroid NENs.
The Inhibitory Role of Rab11b in Osteoclastogenesis through Triggering Lysosome-Induced Degradation of c-Fms and RANK Surface Receptors
- BiologyInternational journal of molecular sciences
- 2020
This work comprehensively clarified a novel function of lysosomes on mediating proteolytic degradation of c-Fms and RANK surface receptors, drastically ameliorated by Rab11b overexpression in RAW-D cell-derived osteoclasts, thereby contributing towards the systemic equilibrium of the bone resorption phase.
Long-term outcome after DNA-based prophylactic neck surgery in children at risk of hereditary medullary thyroid cancer.
- MedicineBest practice & research. Clinical endocrinology & metabolism
- 2019
Morphological, hormonal, and molecular changes in different maternal tissues during lactation and post-lactation
- Biology, MedicineThe Journal of Physiological Sciences
- 2019
This study focuses on the hormonal, metabolic, molecular, and tissue modifications that occur in mammary glands, bone, intestine, and kidneys in the mother during lactation and post-weaning periods.
C Cell and Follicular Epithelial Cell Precursor Lesions of the Thyroid.
- MedicineArchives of pathology & laboratory medicine
- 2017
Putative precursor lesions in the thyroid arising from C cells and follicular epithelial cells are discussed, suggesting that benign follicular lesions may have malignant potential, and there may be a multifocal progression from benign to malignant.
Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms
- BiologybioRxiv
- 2017
An unprecedented investigation of the evolution of neuropeptide copy-number over a period of ~270 million years is performed by analysing sequence data from over fifty ophiuroid species, with reference to a robust phylogeny, and indicates that the composition of neuroPEptide “cocktails” is functionally important, but with plasticity over long evolutionary time scales.
Discovery of novel representatives of bilaterian neuropeptide families and reconstruction of neuropeptide precursor evolution in ophiuroid echinoderms
- BiologyOpen Biology
- 2017
An unprecedented investigation of the evolution of neuropeptide copy number over a period of approximately 270 Myr is performed by analysing sequence data from over 50 ophiuroid species, with reference to a robust phylogeny, and indicates that the composition of neuroPEptide ‘cocktails’ is functionally important, but with plasticity over long evolutionary time scales.
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- Biology, Medicine
- 1964
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- MedicineLancet
- 1963
THYROID HYPOCALCEMIC PRINCIPLE AND RECURRENT LARYNGEAL NERVE INJURY AS FACTORS AFFECTING THE RESPONSE TO PARATHYROIDECTOMY IN RATS.
- Medicine, BiologyEndocrinology
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- MedicineNature
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A suitable procedure is reported on the development of a suitable procedure to alter selectively the concentration of any ion in blood perfusing an isolated organ.
Evidence for calcitonin--a new hormone from the parathyroid that lowers blood calcium.
- Medicine, BiologyEndocrinology
- 1962
It is found that this explanation is too simple and that there are, in fact, 2 hormones from the parathyroid involved—parathormone, released by hypocalcemia, and a hypocalcemic factor, calcitonin, which is released by hypercalcemia.
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- MedicineThe American journal of medicine
- 1961