Thyroid nodules: time to stop over-reporting normal findings and update consensus guidelines
@article{Hofman2013ThyroidNT,
title={Thyroid nodules: time to stop over-reporting normal findings and update consensus guidelines},
author={Michael S. Hofman},
journal={BMJ : British Medical Journal},
year={2013},
volume={347}
}Brito and colleagues correctly highlight the increased detection of incidental papillary thyroid cancers through computed tomography and ultrasonography, but their suggestion of a randomised trial of immediate treatment versus surveillance is not sensible.1 Such a trial would need large numbers of patients and decades of follow-up, with high cost; it …
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References
SHOWING 1-4 OF 4 REFERENCES
Thyroid cancer: zealous imaging has increased detection and treatment of low risk tumours
- MedicineBMJ
- 2013
Thyroid cancer is the most common endocrine malignancy worldwide and its incidence has increased substantially over the past 50 years, according to the latest Cancer Incidence in Five Continents report.
Occult papillary carcinoma of the thyroid. A “normal” finding in finland. A systematic autopsy study
- MedicineCancer
- 1985
According to the study, OPC can be regarded as a normal finding which should not be treated when incidentally found and in order to avoid unnecessary operations it is suggested that incidentally found small OPCs were called occult papillary tumor instead of carcinoma.
Thyroid nodules: is it time to turn off the US machines?
- MedicineRadiology
- 2008
A well-organized multicenter study evaluating ultrasonographic (US) findings associated with benign and malignant thyroid nodules is presented, looking to establish more specific criteria and ultimately define histologic specificity in distinguishing benign from malignant nodules.
Overdiagnosis in cancer.
- MedicineJournal of the National Cancer Institute
- 2010
The two prerequisites for cancer overdiagnosis to occur are described: the existence of a silent disease reservoir and activities leading to its detection (particularly cancer screening), and the magnitude of over diagnosis from randomized trials.