Thyroid hormones-membrane interaction: reversible association of hormones with organized phospholipids with changes in fluidity and dipole potential.

@article{Iss2013ThyroidHI,
  title={Thyroid hormones-membrane interaction: reversible association of hormones with organized phospholipids with changes in fluidity and dipole potential.},
  author={Blanca Alicia Iss{\'e} and Pablo J Yunes Quartino and Gerardo Daniel Fidelio and Ricardo N. Far{\'i}as},
  journal={Chemistry and physics of lipids},
  year={2013},
  volume={175-176},
  pages={
          131-7
        }
}
Differential scanning calorimetry (DSC), mixed monomolecular layers and fluorescence spectroscopy techniques were applied to investigate the effect of thyroid hormones (THs) on the biophysical properties of model membranes. We found that both 3,3',5-triiodo-L-thyronine (T3) and 3,5,3',5'-tetraiodo-L-thyronine (T4) induce a broadening of the calorimetric main phase transition profile and reduce the transition enthalpy in liquid-crystalline state of dipalmitoylphosphatylcholine (DPPC… CONTINUE READING
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