Thyroid hormones induce hemopoietic pluripotent stem cell differentiation toward erythropoiesis through the production of pluripoietin-like factors.

@article{Sainteny1990ThyroidHI,
  title={Thyroid hormones induce hemopoietic pluripotent stem cell differentiation toward erythropoiesis through the production of pluripoietin-like factors.},
  author={Françoise Sainteny and E Larras-Regard and Emilia Frindel},
  journal={Experimental cell research},
  year={1990},
  volume={187 1},
  pages={174-6}
}
We have previously reported that E pluripoietins are produced in mice after a single 20-mg injection of cytosine arabinoside (Ara-C) and that they are able to initiate the determination of hemopoietic pluripotent stem cells (CFU-S) toward the erythrocytic lineage. However, the mechanism of E pluripoietin release is still unclear. Since the stimulating… CONTINUE READING