Thyroid hormones and deiodinase activity in plasma and tissues in relation to high levels of organohalogen contaminants in East Greenland polar bears (Ursus maritimus).

@article{Gabrielsen2015ThyroidHA,
  title={Thyroid hormones and deiodinase activity in plasma and tissues in relation to high levels of organohalogen contaminants in East Greenland polar bears (Ursus maritimus).},
  author={Kristin M{\o}ller Gabrielsen and Julie Stene Krokstad and Gro Dehli Villanger and D. Dakota Blair and M J Obreg{\'o}n and Christian Sonne and Rune Dietz and Robert J Letcher and Bj{\o}rn Munro Jenssen},
  journal={Environmental research},
  year={2015},
  volume={136},
  pages={
          413-23
        }
}
Previous studies have shown relationships between organohalogen contaminants (OHCs) and circulating levels of thyroid hormones (THs) in arctic wildlife. However, there is a lack of knowledge concerning the possible functional effects of OHCs on TH status in target tissues for TH-dependent activity. The relationships between circulating (plasma) levels of OHCs and various TH variables in plasma as well as in liver, muscle and kidney tissues from East Greenland sub-adult polar bears (Ursus… CONTINUE READING
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