Thyroid hormones and cardiac arrhythmias.

  title={Thyroid hormones and cardiac arrhythmias.},
  author={Narcis Tribulova and Vladim{\'i}r Knezl and Asher Shainberg and Shingo Seki and Tom{\'a}s Soukup},
  journal={Vascular pharmacology},
  volume={52 3-4},
Thyroid hormone plays an important role in cardiac electrophysiology and Ca2+ handling through both genomic and nongenomic mechanisms of action, while both actions can interfere. Chronic changes in the amount of circulating thyroid hormone due to thyroid dysfunction or systemic disease result in structural, electrophysiological and Ca2+ handling remodeling, while acute changes may affect basal activity of cardiac cells membrane systems. Consequently, long-term or rapid modulation of sarcolemmal… CONTINUE READING

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