Thyroid hormone transport in the serum of patients with thyrotoxic Graves' disease before and after treatment.

@article{Braverman1968ThyroidHT,
  title={Thyroid hormone transport in the serum of patients with thyrotoxic Graves' disease before and after treatment.},
  author={L. Braverman and A. E. Foster and S. Ingbar},
  journal={The Journal of clinical investigation},
  year={1968},
  volume={47 6},
  pages={
          1349-57
        }
}
Multiple indices of thyroid hormone binding have been studied in sera obtained from patients with thyrotoxic Graves' disease, before and after treatment, and in sera from a group of carefully matched normal controls. Specimens from patients with thyrotoxicosis displayed a decrease in the thyroxine (T(4))-binding capacities of T(4)-binding globulin (TBG) and T(4)-binding prealbumin (TBPA), an increase in serum protein-bound iodine (PBI), and an increase in both the proportion and absolute… Expand
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Examination of sera collected from patients with thyroid disease revealed that the “uptake” of T3-131I by thyroxine-binding globulin was reduced significantly in hyperthyroidism and increased in myxedema and in pregnancy when compared with values in normal controls. Expand
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