Thyroid hormone receptors bind to defined regions of the growth hormone and placental lactogen genes.

@article{Barlow1986ThyroidHR,
  title={Thyroid hormone receptors bind to defined regions of the growth hormone and placental lactogen genes.},
  author={John W Barlow and Marianne L. Voz and P H Eliard and M Mathy-Harter and P P de NAYER and I. V. Economidis and Alexandra Belayew and Joseph A. Martial and G. G. Rousseau},
  journal={Proceedings of the National Academy of Sciences of the United States of America},
  year={1986},
  volume={83 23},
  pages={9021-5}
}
The intracellular receptor for thyroid hormone is a protein found in chromatin. Since thyroid hormone stimulates transcription of the growth hormone gene through an unknown mechanism, the hypothesis that the thyroid hormone-receptor complex interacts with defined regions of this gene has been investigated in a cell-free system. Nuclear extracts from human lymphoblastoid IM-9 cells containing thyroid hormone receptors were incubated with L-3,5,3'-tri[125I]iodothyronine and calf thymus DNA… CONTINUE READING

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