Thyroid hormone metabolism in obesity

  title={Thyroid hormone metabolism in obesity},
  author={Elio Roti and Roberta Minelli and Mario Salvi},
  journal={International Journal of Obesity},
Serum thyroid hormone concentrations and their metabolic fate are within the normal range limits in obese subjects. Also serum TSH concentrations and its response to TRH are normal, suggesting that tissue availability of thyroid hormones is normally preserved in these subjects. In contrast, during caloric restriction serum T3 concentrations decrease as a consequence of its reduced production rate from peripheral deiodination of T4. Opposite, serum rT3 concentrations markedly increase as a… CONTINUE READING
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