Thyroid hormone as a therapeutic option for treating ischaemic heart disease: from early reperfusion to late remodelling.


Thyroid hormone (TH), apart from its "classical" actions on cardiac contractility and heart rhythm, appears to regulate various intracellular signalling pathways related to response to stress and cardiac remodelling. There is now accumulating experimental and clinical evidence showing a beneficial effect of TH on limiting myocardial ischaemic injury… (More)
DOI: 10.1016/j.vph.2009.11.006