Thyroid hormone and the mitochondrial population in the rat heart.


The effects of the thyroid hormone on the number and protein content of mitochondria were investigated in rat heart. The specific mitochondrial population, determined by direct counting, was estimated to be about 3.7 X 10(11) mitochondria per g wet weight in young hypothyroid male rats (T) and about 2.4 X 10(11) (65%) in euthyroid animals, sex- and age… (More)