Thyroid hormone and immunological studies in endemic goiter.

  title={Thyroid hormone and immunological studies in endemic goiter.},
  author={M. A. Boukis and Demetrios A. Koutras and Athanasios Souvatzoglou and A Evangelopoulou and Maria Vrontakis and Spyridon D. Moulopoulos},
  journal={The Journal of clinical endocrinology and metabolism},
  volume={57 4},
Iodized oil (1 ml im) was given to 58 goitrous patients from a mildly iodine-deficient area in Greece. Goiter size, urinary iodine, and serum T4, T3RU, T3, rT3, TSH, thyroxine-binding globulin (TBG), and thyroid autoantibodies were measured before and 1, 3, and 6 months after the injection. Goiter size decreased. Serum T4 remained relatively constant, but TBG decreased and therefore T3RU and FTI increased. Serum T3 and rT3 initially decreased (P less than 0.001) and then increased at the sixth… CONTINUE READING
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