Thyroid function in critically ill patients.

  title={Thyroid function in critically ill patients.},
  author={Eric Fliers and Antonio Carlos Mugayar Bianco and Lies Langouche and Anita Boelen},
  journal={The lancet. Diabetes & endocrinology},
  volume={3 10},
Patients in the intensive care unit (ICU) typically present with decreased concentrations of plasma tri-iodothyronine, low thyroxine, and normal range or slightly decreased concentration of thyroid-stimulating hormone. This ensemble of changes is collectively known as non-thyroidal illness syndrome (NTIS). The extent of NTIS is associated with prognosis, but no proof exists for causality of this association. Initially, NTIS is a consequence of the acute phase response to systemic illness and… CONTINUE READING