Thyroid function and autoimmunity during interferon beta-1b treatment: a multicenter prospective study.

@article{Durelli2001ThyroidFA,
  title={Thyroid function and autoimmunity during interferon beta-1b treatment: a multicenter prospective study.},
  author={Luca Durelli and Bruno Ferrero and Alessandra Oggero and Elisabetta Verdun and Angelo Ghezzi and Enrico Montanari and Mauro Zaffaroni},
  journal={The Journal of clinical endocrinology and metabolism},
  year={2001},
  volume={86 8},
  pages={3525-32}
}
Thyroid dysfunction and autoimmunity have been reported during type I interferon therapy, namely interferon-alpha for chronic hepatitis or interferon-beta for multiple sclerosis. To define the frequency of thyroid dysfunction and autoimmunity during interferon-beta treatment, 156 multiple sclerosis patients were prospectively followed up by 18 centers for 1 yr after starting interferon-beta-1b treatment. Serial clinical assessments and tests of thyroid and liver function and antithyroid… CONTINUE READING

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