Thyroid dysfunction during interferon alpha therapy for chronic hepatitis C.

@article{Shen2005ThyroidDD,
  title={Thyroid dysfunction during interferon alpha therapy for chronic hepatitis C.},
  author={Lily Shen and Chuong D Bui and Robert Mansberg and Diep D. Nguyen and Sharon Alam-Fotias},
  journal={Clinical nuclear medicine},
  year={2005},
  volume={30 8},
  pages={546-7}
}
Interferon-alpha therapy is well known to induce a wide range of thyroid dysfunction. A 22-year-old woman with chronic hepatitis C developed overt hyperthyroidism while on interferon-alpha and ribavirin therapy. Tc-99m thyroid scintigraphy demonstrated virtually absent tracer uptake consistent with subacute thyroiditis. Ten months after starting antiviral therapy, overt hyperthyroidism recurred. Repeat thyroid scintigraphy revealed diffusely increased tracer uptake throughout the thyroid gland… CONTINUE READING