Thyroid disruption by perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA)

  title={Thyroid disruption by perfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA)},
  author={Francesca Coperchini and Oriana Awwad and Mario Rotondi and Ferruccio Santini and Marcello Imbriani and Luca Chiovato},
  journal={Journal of Endocrinological Investigation},
BackgroundPerfluorooctane sulfonate (PFOS) and perfluorooctanoate (PFOA) are two fluorinated compounds widely used in industry because of their useful chemical characteristics. They were identified as endocrine disruptors due to their ability to interfere with thyroid function. The resistance of PFOA and PFOS to environmental degradation, their bio-accumulation in food chains, and their long half-life raised concern in the scientific community, and several studies were performed with the aim to… 

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