Thyroid cancer review 3: management of medullary and undifferentiated thyroid cancer

@article{Nix2006ThyroidCR,
  title={Thyroid cancer review 3: management of medullary and undifferentiated thyroid cancer},
  author={Paul Nix and A R Nicolaides and Andrew P. Coatesworth},
  journal={International Journal of Clinical Practice},
  year={2006},
  volume={60}
}
This is the last of the three review articles dealing with thyroid cancer. Over 90% of thyroid cancer is of the differentiated type associated with a very good 10‐year disease‐free survival rate. In contrast, the rare forms of thyroid cancer which comprise medullary thyroid cancer arising from parafollicluar C cells, Hurthle cell carcinoma, anaplastic carcinoma, thyroid lymphoma and squamous cell carcinoma are typically associated with a poorer survival rate. Management is based upon small… 
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Postoperative management of thyroid carcinoma.
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Ananplastic thyroid carcinomas (ATC) are aggressive undifferentiated tumors with a very high mortality rates, usually infiltrate into surrounding tissues at the time of diagnosis, and have unfavorable prognosis.
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PET/CT is a valuable imaging test, in the appropriate clinical context, for the management of thyroid cancers, and its evolving value is summarized.
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TLDR
Thyroid cancer (TC) affects more women than men and those of Asian descent, particularly of the rare medullary form of the disease, and environmental exposure to ionizing radiation from natural and artificial sources plays a significant role.
Proper Management of Rapidly Growing Large B-Cell Primary Thyroid Lymphoma, Case Report and Review of Literature
TLDR
Lymphoma of the thyroid gland should be considered in patients with a rapidly enlarging goiter, and if there is any doubt of the diagnosis, open surgical biopsy should be performed to confirm the diagnosis.
" Role of FNAC in Diagnosing Thyroid Neoplasms -A Retrospective Study "
TLDR
The aim of this study is to know the prevalence of thyroid cancer in the past five years and the role of FNAC in its diagnosis as well as knowing the limitations ofFNAC in the definitive diagnosis of malignant neoplasm of the thyroid gland.
Primary Thyroid Lymphoma as A Manifestation of Rapidly Growing Thyroid Causing Progressive Respiratory Distress
TLDR
A 73-year old man with rapidly glowing neck mass had a 6-year history of hypothyroidism-associated with Hashimoto thyroiditis and maintained L-thyroxine replacement and an incisional biopsy of the thyroid grand revealed diffuse large B cell non-Hodgkin’s lymphoma with germinal center B-cell subtype.
Metastatic Medullary Thyroid Cancers: Challenges in Diagnosis with Nuclear Medicine Techniques and the Role of Radionuclide Therapy
TLDR
The review shows that despite all studies there is still no consensus on the importance of nuclear medicine in the diagnosis and treatment of patients with medullary thyroid cancer and the role of each of them in medical care is described.
Recent Progress of Genome Study for Anaplastic Thyroid Cancer
TLDR
This review reviewed the comprehensive genetic alterations in ATC and recent approaches in the context of identifying genomic alterations associated with ATC to put emphasis on the urgent needs of genomic research for the prevention and treatment of ATC.
Anaplastic thyroid cancer – an overview of genetic variations and treatment modalities
TLDR
This work is distributed under the terms of the License http://creativecommons.org/licenses/by-nc/3.0/.
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