Thyroid cancer characteristics in the population surrounding three mile island

@article{Goyal2012ThyroidCC,
  title={Thyroid cancer characteristics in the population surrounding three mile island},
  author={Neerav Goyal and Fabian T. Camacho and Joseph F. Mangano and David M. Goldenberg},
  journal={The Laryngoscope},
  year={2012},
  volume={122}
}
To determine differences in disease characteristics between the thyroid cancer populations in the area around the Three Mile Island (TMI) nuclear power plant and the rest of the state of Pennsylvania. 
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9 Citations
Background Citations
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9 Citations

Incidence of thyroid cancer surrounding three mile island nuclear facility: The 30‐year follow‐up
TLDR
If data 30 years later will change original conclusions, explore thyroid cancer incidence rates near nuclear power plants, and better understand effects of chronic low level radiation are explored.
Altered molecular profile in thyroid cancers from patients affected by the Three Mile Island nuclear accident
TLDR
Next generation sequencing (NGS) was used to identify molecular signatures of radiation‐induced TC in a cohort of TC patients residing near TMI during the time of the accident.
Incidence of thyroid cancer surrounding Three Mile Island nuclear facility: the 30-year follow-up.
TLDR
Thyroid cancer incidence since the TMI accident was greater than expected in the counties analyzed when compared to local and national population growth, which supports a link to chronic low level radiation exposure and thyroid cancer development.
Evaluating for a geospatial relationship between radon levels and thyroid Cancer in Pennsylvania
TLDR
To determine whether there is an association between radon levels and the rise in incidence of thyroid cancer in Pennsylvania, data are analyzed to establish a cause-and-effect relationship.
Increasing incidence of thyroid cancer in the Commonwealth of Pennsylvania.
TLDR
The incidence of thyroid cancer is rising at a faster rate in Pennsylvania than in the rest of the nation, as is the rate of tumors that are larger and higher stage at diagnosis, which suggests that rising disease burden has contributed to the increased incidence.
Characteristics of Thyroid Cancer Patients in Haji Adam Malik General Hospital
TLDR
In the 55–64-year age female group, thyroid cancer is most diagnosed at stage IV with papillary thyroid carcinoma, and thyroid cancer patients are usually found with normal BMI and the nodule size of ≥4 cm.
American Thyroid Association Scientific Statement on the Use of Potassium Iodide Ingestion in a Nuclear Emergency.
TLDR
The purpose is to provide a review and updated position statement regarding the advanced distribution, stockpiling, and availability of potassium iodide in the event of nuclear radiation emergencies in the United States.
Radon Levels in Pennsylvania and the Rise in Incidence of Thyroid Cancer
TLDR
While there is evidence of rising levels of radon as well as thyroid cancer in Pennsylvania, the two do not correlate according to the analysis.
Insights into Genetic and Epigenetic Determinants with Impact on Vitamin D Signaling and Cancer Association Studies: The Case of Thyroid Cancer
TLDR
Focusing on thyroid cancer (TC), it is document that genetic and epigenetic determinants can greatly impact individual response to vitamin D and may outweigh the classical clinical correlative studies that focus on sun exposure/dietary intake factors.

References

SHOWING 1-10 OF 21 REFERENCES
Incidence of Thyroid Cancer in Residents Surrounding the Three Mile Island Nuclear Facility
TLDR
Given the long latency period for the development of thyroid cancer after exposure to low‐level radiation exposure, it is plausible that an increase in thyroid cancer incidence might just now be occurring.
Cancer incidence among residents of the Three Mile Island accident area: 1982-1995.
Abnormalities of the thyroid in survivors of Hodgkin's disease: data from the Childhood Cancer Survivor Study.
TLDR
Assessment of thyroid status in Hodgkin's disease survivors found abnormalities of the thyroid are still extremely common in young adult survivors of childhood HD, particularly among females treated with high doses of radiation to the neck.
Radiation-induced thyroid cancer: What we have learned from Chernobyl
TLDR
It is revealed that environmental exposure to 131l during childhood carries an increased risk of thyroid cancer and the risk is radiation dose dependent, the youngest children are most sensitive to radiation-induced carcinogenesis, and the minimal latent period for thyroid cancer development after exposure is as short as 4 yr.
The Three Mile Island Population Registry.
TLDR
Because the radiation dose from TMI was extremely small, any increase in morbidity or mortality attributable to the accident would be so small as not to be measurable by present methods; however, adverse health effects as a result of psychological stress may occur.
Thyroid carcinoma and hyperparathyroidism after radiation therapy for adolescent acne vulgaris.
TLDR
Patients irradiated for facial acne were older and received a comparatively lower dose of radiation, and mitigating factors suggest a decreased incidence of thyroid and parathyroid disease in these patients.
Influence of previous radiation exposure on pathologic features and clinical outcome in patients with thyroid cancer.
TLDR
Patients who have been exposed to radiation have more aggressive disease and worse clinical outcome than other patients with thyroid cancer.
Post-Chernobyl thyroid carcinoma in Belarus children and adolescents: comparison with naturally occurring thyroid carcinoma in Italy and France.
TLDR
The analysis of Belarus thyroid cancer patients less than 21 yr old showed that the post-Chernobyl increase in thyroid carcinomas involved both children and, to a much lesser extent, adolescents, and strongly suggest that this age group should be carefully monitored in the future.
Prognostic relevance of previous exposure to ionizing radiation in well-differentiated thyroid cancer
TLDR
Ionizing radiation increases risk for well-differentiated thyroid cancer (WDTC) but not adverse cancer behavior, and surgeons should be aware of the high incidence of microcancer among patients with previous exposure to radiation.
Mortality among the residents of the Three Mile Island accident area: 1979-1992.
TLDR
The mortality surveillance of this cohort does not provide consistent evidence that radioactivity released during the TMI accident has a significant impact on the mortality experience of this cohorts to date, however, continued follow-up of these individuals will provide a more comprehensive description of the morbidity and mortality experience.
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