Thyroid binding globulin deficiency.

Thyroid hormones circulate in the blood stream mostly bound to a set of plasma proteins which widely differ in their concentration and affinity for the hormones. The three major transport proteins are thyroxine (T4) -binding globulin (TBG), T 4 -binding prealbumin (TBPA), and albumin. TBG encoded by the TBG gene on chromosome Xq22 is the major transport… (More)